Name and Surname: Mario Vincenzo Di IorioDate and place of birth: 15th August 1975, Lucera, FG (ITALY)Work Address: Molecular Medicine Department, University ofPadova, Via Gabelli, 63, 35121 Padova46 Pubblications; 2186 Citations, H-INDEX: 182003 Scuola di Specializzazione in “Genetica Applicata” (3 years post-doctoraldegree) at University of Rome “La Sapienza”, Italy (70/70 with honors).1999 Italian degree in Biological Science (5 years course) at University of Rome“La Sapienza”, Italy (110/110 with honors).1994 Maturita’ Classica at Liceo Ginnasio Statale “R. Bonghi” (Lucera, FG).AWARDS, HONORS, POSITIONS AND WORK EXPERIENCE2021 Associate Professor of Genetic and Microbiology at the Department ofMolecular Medicine, University of Padua2020 Managing Biologist (Level I), Clinical Genetics Unit, University Hospitalof Padua.2018 Renewal of AFM Grant (20687): “Advanced therapy medicinal productsfor the treatment of ocular defects in Ectrodactyly-Ectodermal Dysplasia-Clefting (EEC) syndrome”.2018 Recipient of the grant from the Italian Ministry of Health (RF-2016-02361159): “Advanced therapy medicinal products for the treatment ofocular defects in Ectrodactyly-Ectodermal Dysplasia-Clefting (EEC)syndrome”.2017 Award of National Academic Scientific Qualification to the functions ofassociate professor for “Genetica (05/I1)” and “Scienze delle professionisanitarie e delle tecnologie mediche applicate (06/N1)”.2017 Recipient of AFM Grant (20687): “Advanced therapy medicinal productsfor the treatment of ocular defects in Ectrodactyly-Ectodermal Dysplasia-Clefting (EEC) syndrome”.2015-2018 Member of the “Technical and Sanitary Committee” of the Ministry ofHealth, Roma.2015 Recipient of ex-60% funds (60A07-5935/15): "Accelerated ageing anddefects in proliferation, differentiation and stratification of p63-mutant-stem cells are restored through a siRNA-based approach: a promisingtherapeutic option for corneal disorders in EEC patients".2015 Recipient of the grant “Progetti di Ricerca di Ateneo” (PRATCPDA159895): “Promising gene-based therapeutic approaches to correctocular surface disorders in EEC patients”, University of Padova.2014 Recipient of ex-60% funds (60A07-4372/14): "Gene therapy approachthrough siRNA against p63 mutants to correct ocular surface disorders inEctrodactyly-Ectodermal displasya-Clefting (EEC) syndrome".2014: Collaborator of the grant “Progetti di Ricerca di Ateneo” (PRATCPDA132881): “Innovative method for the treatment of total limbal stemcells deficiency through a tissue-engineered hemicornea: animal model”,University of Padova.2013 Recipient of the grant from the Associazione RP Triveneto: “RetinitisPigmentosa: clinical and molecular diagnosis of disease genes throughNext Generation Sequencing (NGS) and developing of innovative cell andgene therapy strategies.”.2013-present Member of the Ethics Committee of “Istituto Oncologico Veneto-IRCCS”(IOV), Padova.2013-present Adjunct professor of Genetic and Microbiology at Molecular MedicineDepartment, University of Padova.2012-present Executive Biologist (Level I), Microbiology and Virology Unit, AziendaOspedaliera, Padova: co-responsible of the Quality Management.2012-2016 Collaborator and Quality Control consultant at the Cell Factory ofFondazione Banca degli Occhi del Veneto-Onlus (Venice, Italy).

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1. Advanced Therapy Medicinal Products for the Treatment of Ocular Defects in Ectrodactyly-Ectodermal Dysplasia-Clefting (EEC) Syndrome through Viral and/or Non-Viral Gene Therapy Approaches against p63 gene. 2. Tissue Engineering and Stem Cell-Based Therapies for the Treatment of Patients Affected by Bilateral Limbal Stem Cell Deficiency: Preparation of Hemicorneas Obtained by Oral Mucosa Stem Cells expanded on stromal scaffolds (human keratoplasty lenticules) according with good manufacturing practices (GMPs).?3. Molecular Diagnosis of Gene Diseases by means of Next Generation Sequencing (NGS) and Development of Innovative Strategies Based on Cell and Gene Therapies for Retinal Diseases.?